Reproduction steps:

1. Open the attached project “ReproProject“
2. Open Project Settings window (Edit → Project Settings)
3. In XR Plug-in Management → OpenXR subsection, check or uncheck any of the settings available (for example, enable “D-Pad Binding“ feature) inside the OpenXR Feature Groups section
4. Reopen the project
5. Open Project Settings window again, open the XR Plug-in Management → OpenXR subsection
6. Observe the result

Expected result: Settings are saved, the enabled feature is shown enabled
Actual result: Change of settings were not saved, feature is shown as disabled

Reproducible in: 1.8.1 (2022.3.59f1) 1.14.0 (2022.3.59f1, 6000.0.40f1, 6000.1.0b8, 6000.2.0a5)

Reproducible on: Windows 11
Not reproducible on: No other environments tested

Notes:
- “Depth Submission Mode” setting is located in the OpenXR subsection
- User noted: As the settings are not saved, the file Assets/XR/Settings/OpenXR Package Settings.asset has no changed values as observed through the version control
- After switching to Build Profiles tab and back to Project Settings the feature is shown as enabled (not applicable to 2022.3.59f1)