Repro steps:
1) Open the project
2) Click on the brickwall object - notice it is compressed (text in preview window)
3) Go to Preferences and make sure Compress Assets On Import is turned off
4) Switch platforms few times and after every switch - click on the brickwall texture
5) Notice that everytime it's compressed

Expected result: after the switch it should say Not yet Compressed

Reproduced in: 5.4.0b2; 5.3.1p3
Not reproduced in: 5.2.3p3
Regression introduced in 5.3