Steps to reproduce:

1. Create a new project

2. Open File > Build Profiles and add a new iOS or tvOS Build Profile

3. Select the added Profile

4. Press the "Customize player settings" button

5. In "Other Settings," set "Target SDK" to "Simulator SDK"

6. Try changing the "Simulator Architecture" option

Actual results: It's impossible to select "Simulator Architecture"

Expected results: It's possible to select one of the options - X86-64, ARM64 or Universal

Reproducible with versions: 6000.0.b16, 6000.0.19f1

Not reproducible with versions: 6000.0.b15 - Custom Player Settings are not available

Can’t test with versions: 2021.3.43f1, 2022.3.46f1 - Build Profiles feature is not available 

Tested on (OS): 

MacBook Pro, apple M1 Max, Sonoma 14.6.1
Notes:

• Reproducible with both tvOS and iOS Build Profiles
• If the Profile is closed and reopened or added additional one, it's possible to select these options. However, these options remain active even if "Target SDK" is set to "Device SDK"
• If it's switched to a new Profile, then selecting the "Simulator Architecture" option becomes possible, but it becomes impossible if "Device SDK" is set as the "Target SDK"