Reproduction steps (might need 2 screens):
1. Open project attached (UnityJump.zip)
2. Open scene "Scene_SP_BattleEncounter"
3. Make sure to monitor your memory usage. (Task manager will be enough)
4. Move mouse over scene (moving in circles will be enough) for about 5-15 seconds or until error Assertion failed on expression: 'SUCCEEDED(hr)' appears.
5. Move mouse away from scene.

Expected result: Moving mouse over scene will have no unpleasant outcomes.
Actual result: Memory leak appears, possible crash of Unity, others programs and pc itself.

Note: Gif attached for reference.
Turning off scene lightning seems to make this issue disappear. Also while using profiler with GPU Usage memory leak disappears.
Deleting all scripts did not fixed this problem.
Might appear only on one monitor so if you can not reproduce problem on one monitor, transfer scene window to another.
Sometimes you need to select objects and then move mouse over scene.
Were not able to reproduce on new scene.

Reproduced on: 5.5.0f3, 5.5.0p4, 5.6.0b3.
Referring to user it is regression that was introduced in 5.4