Reproduction steps:
1. Open the user's attached project
2. Open scene "Test Scene"
3. Go to File > Build Settings...
4. Press "Add Open Scene" and then "Build And Run"

Expected result: The Shader is displayed after starting the scene
Actual result: The scene opens without displaying the Shader

Reproducible with: 10.2.2 (2020.2.0b12), 11.0.0 (2021.2.0a3), 12.0.0 (2021.2.0a7)
Could not test with: 10.1.0 (2020.2.0b12, shader breaks after downgrading)

Reproduced with:
MacBook Air (Retina, 13-inch, 2019), Intel UHD Graphics 617 1536 MB, macOS 10.15.7

Could not reproduce with:
MacBook Pro (16-inch, 2019), AMD Radeon Pro 5500M 8 GB, Intel UHD Graphics 630 1536 MB, macOS Catalina 10.15.7
iMac (Retina 5K, 27-inch, 2017), Radeon Pro 580 8 GB, macOS 11.2.3

Note:
- The issue is not reproducible in the Editor
- Not reproducible on Windows
- Reproducible on macOS with Mono and IL2CPP